"The bard of biological weapons captures the drama of the front lines."
–Richard Danzig, former secretary of the navy

The first major bioterror event in the United States — the anthrax attacks in October 2001--was a clarion call for scientists who work with "hot" agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of USAMRIID, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.

Peter Jahrling, the top scientist at USAMRIID, a wry virologist who cut his teeth on Ebola, one of the world's most lethal emerging viruses, has ORCON security clearance that gives him access to top-secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox – and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers—one at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using the techniques of genetic engineering to create a new superpox virus – a smallpox that is resistant to all vaccines.

USAMRIID went into a state of Delta Alert on September 11th and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government's response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents.

Jahrling is leading a team of scientists doing controversial experiments with live smallpox, reawakening the virus at the CDC. Preston dramatizes this work and the conflict it has provoked within the scientific community, and he explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.

Advance Praise for The Demon in the Freezer

"Richard Preston has brought us another book that reads like a top-notch thriller. Would that it were fiction. As the movie unfolds in your mind, remember this: It can happen here."
-- Laurie Garrett, author of The Coming Plague

"The Demon in the Freezer is fascinating, frightening, and important. It reads like a thriller, but the demons are real. Richard Preston has a 'black patent' on this kind of reporting and storytelling. He is the only writer on the scene who can make the inside story of biological weapons so darkly entertaining. Read this book and pray that its heroes can lock the demon back in the freezer."
-- Jonathan Weiner, author of The Beak and the Finch

"It reads like a thriller, but the demons are real. Richard Preston has a 'black patent' on this kind of reporting and storytelling. He is the only writer on the scene who can make the inside story of biological weapons so darkly entertaining."
--Jonathan Weiner

"This book will give you nightmares. ... Richard Preston does for smallpox what he did for the deadly Ebola virus in his 1994 best seller, "The Hot Zone": by jump-cutting among narrative strands, he turns a story about science and medicine into a theme-park ride of a thriller."
-- Michiko Kakutani, The New York Times

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